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Behavior Change Providence, Rhode Island saw a decrease in current tobacco use among high school students after its flavor restriction was enforced.56 Use of any tobacco products by youth in Providence decreased from 22.1% in 2016 to 12.1% in 2018

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Multiple sequences were rapidly compared by applying MUSCLE software (Version 3.8.31, to attain the phylogenetic relationships of all representative sequences of OTUs.Finally, the data of various samples were normalized to the sample with the smallest data size