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doi: 10.1189/jlb.1008587 155

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Systems toxicology analyses detected biological effects of nicotine exposure, which included up-regulation of the xenobiotic-metabolizing enzymes CYP1A1 and FMO3 in the lung and metabolic effects, likely interlinked with a generalized stress response to nicotine present in the exposure aerosols [34]

Under todays ruling, those existing products get the broader any person adversely affected standard that would, in theory, be reserved for products that hadnt gone on sale yet

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