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Smooth muscle lacks these caffeine-sensitive calcium- release channels, so there is no contraction.132 Skeletal muscle, however, is rich in calcium-release channels, and thus caffeine can cause contraction or spasm.133 In fact, the sensitivity of muscle tissue to caffeine has been used by veterinarians to predict muscle damage from strenuous running

Four years ago, the makers of Marlboro cigarettes, Altria Group, Inc., spent $16 million to beat a ballot measure to increase taxes on tobacco products

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