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Here, we report that the acute or delayed nasal exposure of acrolein, apart from cigarette smoke but at concentrations similar to that found in cigarette smoke, resulted in increased neuropathic pain behaviors in a rat model of contusion SCI

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Methods Study overview Fifty-nine otherwise healthy adults, who were in one of four categories, completed the study and had usable data: HIV-/Smok- ( n = 16), HIV-/Smok+ ( n = 14), HIV+/Smok- ( n = 18), and HIV+/Smok+ ( n = 11)