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Youd think that smoking is something that football left behind decades ago, like the culture of sinking seven or eight pints the night before a match

In general, this means that GEE models the population average, not providing details about between-cluster (in this case, individuals) variability (such as random effects in mixed-effect models)

People with Crohn's who smoke may find that they: Have more severe symptoms and complications such as strictures and fistulas Have more flare-ups than normal people Require more steroids and stronger drugs such as immunosuppressants and biologics to cure

The clouds and flavor come from heating those liquid ingredients and turning them into vapor/smoke

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