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Funding This study was supported by grants from the National Heart, Lung, and Blood Institute of the National Institutes of Health (R01 HL142511) to YT and MLG, the US Food and Drug Administration (FDA), and the National Cancer Institute Grant U54CA228110 to MLG, and P30CA016056 involving the use of Roswell Park Core facilities

A pooled analysis of 751 population-based studies with 4.4 million participants