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In the US alone, 54,000 people are expected to be diagnosed with oral cancer this year, and guess what

A note below the figure says, Rx = prescription. A second note below the figure says, General Substance Use includes any illicit drug, alcohol, and tobacco product use

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The FDA has only approved the marketing of a few dozen products, making it unclear to retailers and the public of the regulatory status of a large number of products, such as those for which a PMTA was never filed, those for which a PMTA was timely filed and the application is awaiting an order, and those for which a PMTA was denied but the application remains pending for legal reasons