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Preclinical models, tumor evolution throughout the lifespan, genetic associations with tumor phenotype, and a brief history of interventional clinical trials are also discussed

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Nat Rev Drug Discovery 20:309325 Narita Y, Arakawa Y, Yamasaki F, Nishikawa R, Aoki T, Kanamori M, Nagane M, Kumabe T, Hirose Y et al (2019) A randomized, double-blind, phase III trial of personalized peptide vaccination for recurrent glioblastoma

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