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The sequestration of the nondeformable spherocytes in the spleen and their subsequent phagocytosis by the splenic macrophages is responsible for anemia and splenomegaly

A typical split protocol would involve 0.25 mg in the morning and 0.25 mg in the evening

M.ColellA.Garcia-RuizC.KaplowitzN.Fernandez-ChecaJ

Month 2-3 : Most patients are by now 100% healed and can continue all regular activities

Accordingly, it is reported that glutamate supplementation of up to 1-2 mM enhanced IFNy and IL-10 secretion by activated adult human peripheral T cells in vitro , whereas secretion of T H 2 cytokines IL-4 and IL-5 was unaffected (180)