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The regulatory mechanisms for ferroptosis mainly focus on aspects such as the glutamate antiporter (System Xc-), GSH metabolism, regulation of the activity of GPX4, and ROS generation (12)

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EPO is responsible for increasing blood oxygen-carrying capacity by stimulating erythropoiesis

Krenkel O, Puengel T, Govaere O, Abdallah AT, Mossanen JC, Kohlhepp M, Liepelt A, Lefebvre E, Luedde T, Hellerbrand C, Weiskirchen R, Longerich T, Costa IG, Anstee QM, Trautwein C, Tacke F