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Agents Actions (1992) 36:99118

J.UrsiniF

2 Basic concepts and molecular mechanisms of ferroptosis 2.1 The concept of ferroptosis and comparison with other cell death mechanisms Ferroptosis is a recently proposed concept of cell death driven by iron-dependent lipid peroxidation

The primary end point was PFS, while the secondary end points were OS, response rate, and safety.[22][Level of evidence B1] The median PFS in the lenvatinib group was 18.3 months versus 3.6 months in the placebo group (HR progression or death , 0.21