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Important: Serum copper alone doesn't tell the full story

One is that erastin binds to mitochondrial VDAC2/3 in BJeLR cells and induces ferroptosis with aberrant ROS generated by the mitochondrial oxidative respiratory chain (Yang et al., 2020)

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In contrast to non-viral systems, viral vectors used for therapeutic applications are typically engineered by deleting viral replication and pathogenicity genes and replacing them with therapeutic transgenes [63]