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confirmed that TFAP2C regulated GPx1 expression by directly binding to the GPx1 promoter, which contains an AP-2 regulatory region, and the methylation of the CpG island in the GPx1 promoter region prevented the binding of TFAP2C by encompassing the AP-2 regulatory region [81]

CSCs, characterized by elevated TCF4 and ATP7B expression, exhibited reduced labile copper pools and increased resistance to cuproptosis

15 16 Sermorelin, under the brand name Geref, was FDA-approved for pediatric growth hormone deficiency but was later taken off the market for non-medical reasons

Following this, we carried out a Src knockdown in DDR2-OE cells

Perfusions were performed at 6, 7.5, and 9 months of age, with the proliferation marker BrdU applied 6 weeks earlier