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Phagophores nucleate and expand by integrating membranes from multiple sources such that they become sealed double-membrane autophagosomes that engulf various substances 23

Protein S-glutathionylation reactions as a global inhibitor of cell metabolism for the desensitization of hydrogen peroxide signals

First, its interplay with lipid metabolism: surplus pyruvate generated through glycolysis is converted to acetyl-CoA, which can enter lipid biosynthetic pathways and promote the synthesis of fatty acids, particularly PUFAs

Similarly, punicalagin promotes nuclear factor erythroid 2-related factor 2 (Nrf2) signaling, which boosts antioxidant defenses while decreasing apoptosis and inflammation (Al-Khawalde et al