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Then, what is the role of Nrf2 in promoting cell proliferation in the absence of external insults

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Researchers have observed that it stimulates growth hormone release from anterior pituitary somatotrophs without significantly affecting cortisol, prolactin, or adrenocorticotropic hormone (ACTH) levels a selectivity profile that has made it one of the most widely studied GHRPs in preclinical research

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Advantages include muscle and metabolic profile, but there are risks to balance against, especially long-term, where the connection to malignancy is uncertain