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Tetrahydrofolic acid, methyltetrahydrofolate, and other folic acid congeners are essential for the maintenance of normal erythropoiesis and are also required cofactors for the synthesis of purine and thymidylate nucleic acids

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3.2.1) (6, 15, 124, 132), with consequent oxidative and nitrosative modification of key proteins involved in maintenance of neuronal cell potentials (138), Ca 2+ signaling (139, 237), neurotransmission and associated synaptic remodeling (124, 238), and long-term potentiation (LTP) (239) and survival of synapses themselves (234, 235, 240)

High-temperature cooking or prolonged storage can significantly reduce the amount of active antioxidants in your food

For example, it has been shown that the error-related cortical potentials during anti-saccades are reduced in subjects with focal cerebellar lesions [343] and that the magnitudes of the potentials correlate with the volume of Crus I and II in patients with cerebellar degeneration [344]