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However, the hepatic levels of cysteine and its metabolites, such as hypotaurine, taurine, and GSH, are increased despite inhibition of the transsulphuration of homocysteine to cysteine in non-obese type-2 diabetic Goto-Kakizaki rats [57]

This enables mutations conferring partial resistance to become fixed in the population, providing leverage for further secondary resistance mutations 193

Manage Stress Since stress can deplete glutathione levels, consider practices such as meditation, yoga, or deep breathing exercises to manage stress effectively

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