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Interestingly, investigations on females with diminished ovarian reserve have shown that the supplementation with IGF increases LHR, FSHR, and GHR expression in isolated human granulosa cells

Proc Natl Acad Sci U S A (2009) 106(23):91804.10.1073/pnas.0903111106 55 AminK

Gln was significantly associated with BPRS total score (rho = 0.363, p = 0.023) across groups, and a similar relationship was present in the long (rho = 0.433, p = 0.050) both not short ( p = 0.335) and illness duration groups

The ability of MSCs to promote tissue regeneration, decrease inflammation, and differentiate into Schwann cells in specialized in vitro conditions 7 support the hypothesis that these cells may positively influence nerve regeneration outcomes in the setting of limb transplantation

It is important to note that both human and hamster P-gp contain the same epitope sequence for C219 mAb [26], hence differences in antibody antigen binding is not responsible for differences in P-gp signal in the two cell lines