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Interestingly, a small trial in 30 premenopausal women found that daily multivitamin supplementation for ten weeks did not improve overall mood, but when the supplement also contained 7 mg/day of zinc (RDA=8 mg/day), the authors noted significant improvements in two components of POMS: the anger-hostility and the depression-dejection scores (140)

Grady C, Bedarida G, Sinaii N et al

Structure of rat monoamine oxidase A and its specific recognitions for substrates and inhibitors

The potential gut microbiota-mediated treatment options for liver cancer

In dogs with MDR1 mutations, which have defects in transporter operations, the central nervous system becomes more penetrated and has a greater risk of neurotoxicity after an oral dose (87)