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doi: 10.1016/j.jacc.2021.09.1369 67

Z.DikmenZ

PMID: 299 AroraRRaiPKRamanB

Collectively, these results establish that the timing of anti-CD25 co-administration critically determines the magnitude of GC enhancement, with pre-immunization (day -1) and co-administration (day 0) interventions emerging as the optimal therapeutic window for maximizing GC B cell, Tfh cell and Tfh:Tfr polarization