acetaminophen toxicity glutathione N-Acetylcysteine & Paracetamol Poisoning Rescue Too much paracetamol = dangerous

Too much paracetamol = dangerous because of how your liver processes it. *Normal dose:* About 90 95% gets broken down safely by glucuronidation + sulfation non toxic stuff you pee out. *The problem SUPER EASY MEMORY Too much Tylenol More NAPQI Less glutathione Liver dies NAC More glutathione Liver saved Silymarin prevents acetaminophen induced hepatotoxicity via up regulation of the glutathione conjugation capacity in mice ScienceDirect acetaminophen toxicity glutathione step 1 in Children: Diagnosis, Clinical Assessment, and Treatment of Acute Overingestion Pathways for acetaminophen metabolism. Acetaminophen Acetaminophen Toxicity Poisoning

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