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2.2 Mechanism of ferroptosis The sources of lipid ROS that induce ferroptosis are multifaceted, and lipid peroxidation pathways and iron metabolism are increasingly considered to be involved in the ferroptosis process (14) (Figure 1)

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doi: 10.3390/nu14010143 145 TongL.FengQ.LuQ.ZhangJ.XiongZ

Hence, cells might also need to maintain the balance between GSH and GSSG to limit free FA and to prevent redox disruption

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