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And Qinghai Provincial Key Laboratory of Tibetan Medicine Pharmacology and Safety Evaluation, Northwest Institute of Plateau Biology, Chinese Academy of Science

Cell Death Dis 14:18 Cao G, Miao H, Wang YN, Chen DQ, Wu XQ, Chen L, Guo Y, Zou L, Vaziri ND, Li P, Zhao YY (2022) Intrarenal 1-methoxypyrene, an aryl hydrocarbon receptor agonist, mediates progressive tubulointerstitial fibrosis in mice

This is why insulin, growth hormone, and many other peptide-based medications require injectionoral administration would result in degradation before the compound reaches systemic circulation

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Thus, we were unable to study the effect of CK1-phosphorylation on the nucleo-cytoplasmic shuttling of TDP-43 since it has been suggested that CK1 inhibition could ensure the physiological nuclear compartmentalization of TDP-43 and regulated the nucleo-cytosol translocation of TDP-43 [3]