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Though the results are inconsistent from population studies, an interconnection between the pathogenesis and catalase may still be possible as scattered demonstrations are reported in the literature

DNA damage repair: PARP1 consumes NAD+ to detect and repair DNA strand breaks

Sep 1 2013;140(1-2):31-8

Notably, these pathways demonstrate significant cross-talk, where dysfunction in one system often amplifies perturbations in others

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