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In addition to limited absorption via the IF, the intake of high-dose supplements leads to passive diffusion, i.e., the vitamin can freely enter the bloodstream without IF binding and receptor uptake

Wellness 14 July 2025 8 min read Injecting B12 into fat: the 4 body areas that work best By Alaiyka Parvez Owner, CoLaz Aesthetics Clinic The short version Injecting B12 into fat means placing it in the subcutaneous layer, the soft fatty tissue between your skin and muscle, rather than deep into a muscle

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The first few weeks produce modest changes as the dose titrates up