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Significantly, the antimalarial potency of these compounds correlated well with their ability to disrupt erythrocyte redox balance in vitro (and slightly less strongly in vivo in mice), leading the authors to conclude that erythrocyte enolase is likely the common target that links these two characteristics

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Cell Rep 44(1):115172 Stoolman JS et al (2025) Mitochondria complex III-generated superoxide is essential for IL-10 secretion in macrophages

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