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Description

From these five studies, in two, in vivo delivery into the target tissue, brain or brain tumor, was evaluated in any capacity

In this model, 0.15 mg/kg BID was defined as the minimal efficacious dose, corresponding to ALG-055009 plasma C max of 82.5 ng/mL, AUC 0-24 of 515 ngh/mL and C min of 2.01 ng/mL