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The study included both in vivo analysis from two phase 2 clinical trials and in vitro experiments using primary human hepatocytes

MT2A is the most abundant one in heart, smooth muscle, and endothelial cells, whereas MT1E and MT1X are with less abundance but still significantly expressed, suggesting their important functions in cardiovascular physiology

Malekahmadi M, Firouzi S, Rezayi M, Ghazizadeh H, Ranjbar G, Ferns GA, et al

Finally, in a very preterm IUGR model, single uterine artery ligation resulted in increased fetal cortisol levels without maturational pulmonary effects (289)

10.1007/978-3-540-33823-9_7 44 HuchoT