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Description

10.1051/limn/2004015 15 BeutlerE

Mitochondrial genome editing gets precise

Methods 76 JayakumarA

The honest takeaway

The majority of alcohol is oxidized in the cytosol by aldehyde dehydrogenase (ADH), in peroxisomes by CAT, and in microsomes and mitochondria by CYP2E1 via the microsomal ethanol-oxidizing system (MEOS) before toxic acetaldehyde is further detoxified by mitochondrial aldehyde dehydrogenase 2 (ALDH2) [187, 188]