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Antacids and proton pump inhibitors such as Prilosec, Protonix, Prevacid, Aciphex, Zantac and Pepcid also can lead to B12 deficiency, because they reduce the stomach acid necessary to release the B12 from food

This study provides experimental evidence for the link between oxidative and autoimmune pathways, taking into account the different intracellular compartments and processes

12 Now we recognize that ROS can be generated through mechanisms such as the mitochondrial electron transport chain, the endoplasmic reticulum, and NOX

Interestingly, the researchers found that lymphocytes in these patients had elevated levels of glutathione, which they hypothesize is a desperate, inadequate compensatory response by the cells trying to survive the relentless oxidative avalanche

showed that the accumulation of succinate, that is oxidized by complex II (succinate dehydrogenase), results in mtROS production, seemingly from RET at complex I ( 2.2.2 Monoamine Oxidases A relevant mitochondrial-specific source of ROS is monoamine oxidase (MAO), although its impact on inflammation has been quite overlooked