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Xiang WF, Mu G, hang YZ, et al

NICE Clinical Knowledge Summaries recommend B12 injections for: Pernicious anaemia an autoimmune condition affecting intrinsic factor production Malabsorption syndromes including coeliac disease and inflammatory bowel disease Post-surgical states particularly following gastrectomy or ileal resection Strict vegan diets when oral supplementation proves inadequate, though oral cyanocobalamin is usually sufficient for dietary deficiency Clinical trials demonstrate that B12 injections rapidly improve haematological parameters and neurological symptoms when deficiency is confirmed through blood tests

Hepatology 40 , 69 (2004)

However, a wrinkle-reduction score of 2 was received by 3.3% (Week 4), 10.0% (Week 6), 20.0% (Week 8), and 33.3% (Week 10) of subjects at GSSG sites

The product tested in this experiment was labeled as noni herb powder, but there was no information provided about the specific plant part used, harvesting and processing conditions, or the geographic origin