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Recent studies further indicate that pomegranate can attenuate aggressive cancer phenotypes by reducing breast cancer cell invasion and motility (366, 368) diminishing cancer-associated inflammation (369)and suppressing cellular proliferation, effects that are likely linked to its antioxidant capacity (370)

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607 In functional studies, astrocytes differentiated from stem cells obtained from familial AD showed aberrant Ca 2+ signalling, 608,609 increased production of reactive oxygen species, reduced lactate supply, compromised neuroprotection, and inability to support neurones in co-cultures