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In this review, we summarise the present understanding of cNF pathogenesis including recent studies that propose a putative tumour cell of origin, the identification of mutations in NF1 and other genes in cNF, the role of the tumour microenvironment and endocrine signalling in cNF, and past, recent and ongoing clinical trials for cNF

This week, a patient came into my practice after being in a minor car accident

Proc Natl Acad Sci United States America (2014) 111(39):1421722

A six-month, multicenter observational study enrolled 197 stroke subjects (mean age, 81.5 years) with a progressive decline of their mental health and general confusion and/or stupor who were initially administered citicoline for 5 or 10 days (2,000 mg/day, by intravenous infusion) within a four-month period, and then for 21 days (1,000 mg/day, by intramuscular injection), repeated once after a seven-day washout period (93)

Trichothecenes are considered extremely toxic and have been used as biological warfare agents