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Elevated glutamate levels can play a role in promoting cytotoxic edema by raising intracellular sodium levels and facilitating the movement of water into the cells, subsequently increasing the volume of intracellular fluid (Yi and Hazell, 2006)

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1124 They also ameliorate mitochondrial dysfunction in neurons and glial cells

The staging of hepatic fibrosis at diagnosis is necessary to assess for severity of liver injury and end organ damage in order to better guide clinical management, and in those with advanced fibrosis or cirrhosis, to screen for primary liver cancer

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