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These forms of epigenetic modifications interact with each other to jointly regulate gene expression, playing critical roles in processes such as cell differentiation, development, disease progression, and stress responses [17, 18]

Mitochondrial MTHFD2L is a dual redox cofactor-specific methylenetetrahydrofolate dehydrogenase/methenyltetrahydrofolate cyclohydrolase expressed in both adult and embryonic tissues

This is an intriguing development, as it challenges the conventional understanding of Hcy's role in cellular processes

However, YTHDF1 depletion resulted in decreased DENV viral titers without affecting the viral RNA or protein levels (Supplementary Fig

We thank Stephanie Tribuna for assistance in preparation of this article and apologize to investigators whose work was not mentioned due to space limits