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Safety concerns included uncharacterized immunogenicity (the risk that injected peptides trigger immune reactions), inadequate impurity and endotoxin testing in available raw material, the unresolved free base versus acetate salt form distinction, and, for BPC-157 specifically, an angiogenesis mechanism that raises theoretical cancer-risk concerns for certain patient populations

2.2 Defective energy metabolism and increased oxidative stress in mitochondria To execute energy production and substance metabolism are the main functions of mitochondria ( + to ultimately initiate OXPHOS

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10.1097/01.jnen.0000202887.22082.63 [DOI] [PubMed] [Google Scholar] Crowther R

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