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In the cyclic KD (CKD), periods of the KD and the high-carbohydrate diet are alternated [12]

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There are several reasons why vitamin D improves IR, including its direct action on insulin secretion and signaling (93) and its role in regulating calcium as a second messenger for insulin-mediated processes within cells (109)

doi: 10.1002/jbt.23307 277 TangCLiuJYangCMaJChenXLiuDet al

The on-bench and in vitro experimental studies demonstrate that the characteristic hypercarbon-tetragold(I) multi-center bonding in PAA4 and PAA5 not only guarantees their stability under common physiological conditions, but also facilitates a glutathione (GSH)-triggered prompt and synergetic release of active Au(I) ions in the GSH-overexpressed and acidic microenvironment of human bladder cancer EJ cells