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146 According to previous studies, fluoxetine stimulates c-Fos expression and ERK 1/2 phosphorylation, which in turn promotes BDNF production in astrocytes sorting from GFAP-GFP transgenic mice

Recognition of these electrophysiological alterations is crucial, as they may precede malignant ventricular arrhythmias and SCD

Despite this gap in knowledge, a plausible hypothesis could be formulated that either treatment with exogenous melatonin or interventions aimed at restoring endogenous melatonin secretion might offer potential in mitigating neurodegenerative processes induced by circadian disruption

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In contrast, administering a lower dose of 200 mg/kg NAC was insufficient to prevent mortality (Fig