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10.1159/000346968 19 EFSA NDA Panel (EFSA Panel on Dietetic Products, Nutrition and Allergies) (2015)

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Vials are assembled into multi-vial research kits that can be reconstituted with a suitable sterile diluent immediately before use in line with internal SOPs

Deficiency can occur in certain populations, including older adults, vegans, individuals with pernicious anaemia, those with malabsorption disorders such as Crohn's disease or coeliac disease, people who have had bariatric surgery or gastrectomy, and those on long-term medication such as metformin or acid-suppressing drugs