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In addition, when the UF animal model was being treated with LD the BCL-2 expression in the uterine tissue was significantly decreased with an increase in Bax mRNA expression, thus showing the apoptotic potential of LD in the treatment of UF (Li et al., 2013)

In addition, glutamate shows the highest absolute increase in concentration along lactation, increasing from ~1.25 to 1.75 mM from month 1 to 6 of lactation (64, 75)

In terms of research and development pipeline, the focus of semaglutide product development is primarily on the development of new formulations and the expansion into new indications