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During the ischemic phase, severe hypoxia and nutrient deprivation impair mitochondrial function, leading to a modest increase in ROS production due to limited electron leakage from the dysfunctional mitochondrial electron transport chain (ETC.) (Sen et al., 2024)

In a previous study with preterm infants, significant negative correlations were found between the GPx activity and both SOD and CAT activities, and positive correlation between the activities of SOD and CAT (42)

A cross-sectional study involving 199 HS patients found that more than 60% of men had clinically significant sexual dysfunction (17)

The STAT3 siRNA significantly abolished increases in STAT3, cyclin D1 and CDC25A and decreased the protein expression of GSTP1, but there was no change in p-JAK2

Nat Reviews Endocrinol