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aurantium have been linked to serious clinical adverse events, mostly related to CV issues, including syncope, QT interval prolongation, MI, ischemic stroke, angina, tachycardia, bradycardia, hypotension, vasospasm, ventricular fibrillation, and ischemic colitis (239, 242)

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Alanine and glutamate are often interconnected in the context of nitrogen metabolism, where the amino group from alanine is transferred to alpha-ketoglutarate, resulting in the production of glutamate and pyruvate