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Recently, Lee and co-workers revealed the role of IKK in neuroinflammation, one of the mechanisms of secondary SCI [88, 89]

AGEs, such as acrylamide, may also contribute to elevated levels of endothelial dysfunction, oxidative stress, and inflammation (8, 97)

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Huynh K, McMullen JR, Julius TL et al (2010) Cardiac-specific IGF-1 receptor transgenic expression protects against cardiac fibrosis and diastolic dysfunction in a mouse model of diabetic cardiomyopathy