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Figure 3 Despite these minor concerns, the overall risk of bias was predominantly low, reinforcing the credibility of the included non-randomized studies

F.FerreiraS

Reviews describe regenerative and protective actions, roles in skin regeneration, and modulation of multiple cellular pathways but this is largely mechanistic and preclinical work, not large human efficacy trials

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The observed gain is consistent with prior studies comparing domain-adapted checkpoints to Base-BERT on social-media mental-health tasks, where absolute improvements typically remain below one percentage point once extensive fine-tuning is applied 14,26