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These phenomena appear to be rationale, for example during inflammation, where cells are believed to be exposed to severe oxidative stress, where suppression of glucocorticoid action may potentiate endogenous defense mechanisms and prevent premature termination of the cascade of inflammatory reactions for self-defense

Eur Rev Med Pharmacol Sci (2018) 22(21):7588605

Multiple-windowed detection within a single experiment comes with a drawback: observed oscillations can feature reduced lifetimes due to the discontinuous sustaining

J Neurosci Res 87:18321840 Yang S-H, He J-B, Yu L-H, Li L, Long M, Liu M-D, Li P (2019) Protective role of curcumin in cadmium-induced testicular injury in mice by attenuating oxidative stress via Nrf2/ARE pathway