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Apparently, it is also independent of auxin as auxin response at transcriptional level is still detected in mto2-2 seedlings ( Interestingly, THREONIN SYNTHASE 2 (AT1G72810) may compensate TS1 mutation in mto2 mutant

Gupta, P, Valdebenito-Silva, S, Kumar, G, Chakrapani, P, Oberai, S, Dang, M, Katayama, H, Wang, L , Eugenin, EA, Bhat, KP

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As B12 is a water-soluble vitamin, it's generally considered safe (because any not used will be excreted via your urine), but even so you shouldn't take more than the recommended doses unless recommended to do so by your GP, as some studies have shown possible negative impacts of overdoing it

Chen B, Julg B, Mohandas S, Bradfute SB