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Following its binding with IF, the cobalamin-IF complex promotes hepatic uptake via an active and saturable mechanism called cubilin/AMN receptor-mediated endocytosis

Sci Rep 11:12396 Perez-Riverol Y, Bandla C, Kundu DJ, Kamatchinathan S, Bai J, Hewapathirana S, John NS, Prakash A, Walzer M, Wang S et al (2025) The PRIDE database at 20 years: 2025 update