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& Daley, G

It does not appear to cause serious AEs in test subjects and has been linked to only mild, temporary side effects such as headaches, fatigue, and localized swelling [1]

Where this category of medication is approved and available, its potential role as part of a wider pre-operative medical plan is something I will discuss with the patient and their broader medical team

Experts dont recommend combining trazodone and alcohol

For patients who dont respond to 3-6 months of conservative treatment, correction of extensor mechanism alignment problems (medial plication/lateral release, tibial tubercle osteotomy) and cartilage-oriented surgeries (arthroscopic patellar shaving, drilling of the defect that reaches subchondral bone, facetectomy, tibial tubercle proximal relocation, patellectomy, patellofemoral surface arthroplasty) may be needed.