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The claim that nasal spray delivers equivalent or superior levels to injection is not supported by published data and is not a claim any legitimate researcher has made in print

10.1016/j.schres.2009.03.005 Schizophr

Furthermore, the hypermethylation of promotor regions of circadian-cycle-dependent genes was observed in breast cancer cells [114], and melanoma [117], pan-renal cell carcinoma [118], cervical and esophageal cancer [119], and hepatocellular carcinoma cells [120]