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*Correspondence: [email protected] This article was submitted to Experimental Pharmacology and Drug Discovery, a section of the journal Frontiers in Pharmacology

Signal sequences can be used to facilitate secretion and isolation of secreted proteins or other proteins of interest

It aims to simplify complicated material and highlight areas that need more investigation by integrating our present knowledge of SALs and their sources, biosynthesis, extraction, analysis, pharmacological effects, and molecular processes